We Have Beds Available! Call for Same Day Admission.855-722-6926
We Have Beds Available! Call for Same Day Admission.855-722-6926

Can You Overdose On Muscle Relaxers?

Muscle relaxers or muscle relaxants refer to a group of medications that affect skeletal muscle functioning and reduce muscle tone.

These medications are usually prescribed to alleviate symptoms like muscle spasms, pain, and hyperreflexia. The term muscle relaxant refers to two major drug groups: neuromuscular blockers and spasmolytics. Common types of muscle relaxers include Baclofen, Soma, Lorzone, Cyclobenzaprine, Dantrium, and various types of benzodiazepines. As with other medications, a major concern among prescribed patients is the risk of overdose, so today, we’re looking into whether you can overdose on muscle relaxers. 

Questions about our Facilities or Programs?

Our admissions coordinators are available 24/7 to answer any questions you may have as you consider whether treatment at Banyan is right for you or your loved one.

How Do Muscle Relaxers Work?

Muscle relaxers work by reducing stiffness and tension in the muscle, reducing pain and discomfort. Muscle relaxants like Baclofen, diazepam, methocarbamol, and tizanidine act on the central nervous system (CNS).

Specifically, muscle relaxers bind to acetylcholine receptors (AChR) in the brain. Acetylcholine is the primary neurotransmitter in the parasympathetic system, which plays a major role in smooth muscle contraction, blood vessel dilation, increasing bodily secretion, and reducing heart rate. 

Muscle relaxers are designed to reduce cramping, spasms, stiffness, and other similar muscular issues that may produce pain or discomfort.

Causes of Muscle Relaxant Overdose

To be clear, yes, you can overdose on muscle relaxers. Although a muscle relaxer overdose is different from a heroin or cocaine overdose, it’s both risky and possible, nonetheless.

Muscle relaxant overdose symptoms can occur if the person takes a higher dose than prescribed. Other factors that can increase one’s risk of a muscle relaxer overdose include increased tolerance, age, gender, polysubstance use, and recreational use. 

Tolerance and dependence can occur when taking muscle relaxers regularly. When someone has developed tolerance to a drug, they may require a higher dose to experience the same effect. 

Additionally, physical drug dependence occurs when the brain and body are unable to function normally without the drug. As tolerance and physical dependence grow, a person taking muscle relaxers may increase their dose to experience relief from their symptoms, thus increasing their risk of overdose. 

Age is a big contributing factor to overdosing on muscle relaxants, as those who are elderly are more likely to be heavily affected by higher doses of these drugs due to a slowed metabolism. This also means that the elderly are more likely to overdose on lower doses of muscle relaxants compared to younger adults. 

Drinking alcohol with muscle relaxants can also affect the medication’s efficacy, causing the person to take higher doses to feel relief from their symptoms. This also increases the person’s potential for overdose. 

Getting into treatment is easy with our free insurance verification

"*" indicates required fields

This field is for validation purposes and should be left unchanged.

What Happens When You Overdose On Muscle Relaxers?

How many muscle relaxers it takes to OD depends on the factors mentioned above, as well as the person’s regular dose and how long they’ve been taking the medication. Generally, taking 3 to 5 times the prescribed dose of any drug can lead to overdose. 

This means that adults who are supposed to take 30 mg of Cyclobenzaprine per day can overdose if they take 60 mg or more. Common signs of muscle relaxer overdose include: 

  • Respiratory depression or trouble breathing
  • Hallucinations
  • Sedation
  • Confusion and lethargy 
  • Flushed skin
  • Dilated pupils
  • Coma 
  • Seizures
  • Hypotension (low blood pressure)
  • Drowsiness or dizziness
  • Rigidity or stiffness


Muscle relaxant overdose symptoms may also vary depending on the dose and type of medication taken. Combining muscle relaxants with other drugs, such as alcohol, can intensify the side effects of muscle relaxants, making overdose symptoms more severe and dangerous. 

If you recognize the signs of muscle relaxer overdose in anyone, call 9-1-1 immediately. This is a dangerous reaction that requires medical attention. 

Help for Muscle Relaxer Abuse

  Although overdose is unlikely in people who take muscle relaxers as prescribed, it can occur accidentally if the person happens to drink alcohol or take another medication with the muscle relaxant still in their system. Additionally, muscle relaxers are also addictive for some people.

Muscle relaxant abuse refers to taking higher doses than prescribed, taking them without a prescription, and mixing them with other drugs or alcohol. Engaging in muscle relaxer misuse can not only lead to addiction but also increase your risk of overdose. 

If you or someone you care about has developed an addiction to drugs or alcohol, our Palm Springs, CA, drug rehab can help you take your first step towards recovery. Starting with medically monitored detox, we slowly wean patients off of their substance of choice while providing medication (as needed) to manage their withdrawals and drug cravings. 

Following detox, patients can then move onto our prescription drug addiction treatment program or any of our other rehab programs, depending on the form of addiction they have. During treatment, patients work with our counselors individually and in group settings to learn more about their substance use disorders, connect with others in the recovery community, and learn how to sustain their sobriety after rehab. 

Recovery is possible no matter how severe your addiction is. For more information about our California drug treatment programs, call Banyan Treatment Centers today at 888-280-4763.

Related Reading: 
The Effects of Alcohol on Muscles & Joints
Puffy Hand Syndrome and Drug Abuse

Alyssa, Director of Digital Marketing
Alyssa, Director of Digital Marketing
Alyssa is the National Director of Digital Marketing and is responsible for a multitude of integrated campaigns and events in the behavioral health and addictions field. All articles have been written by Alyssa and medically reviewed by our Chief Medical Officer, Dr. Darrin Mangiacarne.