Denial Substance Use
A psychological defense mechanism in which a person refuses to acknowledge or accept the existence or severity of their addiction. Denial is one of the primary barriers to seeking treatment.
Depressants Medical
Substances that slow central nervous system activity, producing sedation, reduced anxiety, and impaired coordination. Includes alcohol, benzodiazepines, and barbiturates.
Depression Mental Health
A common and serious mood disorder characterized by persistent sadness, loss of interest, low energy, and impaired function. Major depressive disorder frequently co-occurs with substance use disorders — each can trigger or worsen the other.
Detoxification (Detox) Treatment
The medically supervised process of clearing substances from the body while managing withdrawal symptoms. Detox is typically the first phase of treatment and is not treatment in itself — it must be followed by ongoing therapeutic intervention.
Dialectical Behavior Therapy (DBT) Treatment
An evidence-based therapy combining cognitive-behavioral techniques with mindfulness and acceptance strategies. Highly effective for borderline personality disorder, self-harm, suicidal ideation, and substance use disorders.
Dopamine Medical
A neurotransmitter central to the brain's reward and motivation pathways. Most addictive substances hijack the dopamine system, producing surges of pleasure that reinforce drug-seeking behavior and reshape brain function over time.
Drug Misuse Substance Use
Using a substance in a way that differs from its prescribed or intended use, or in amounts that cause harm to the user or others. Drug misuse does not always indicate addiction but can precede it.
Drug Tolerance Substance Use
A progressive state in which the body adapts to a substance, requiring increasingly higher doses to achieve the same effect. Tolerance is a key marker of developing physical dependence.
DSM-5 Mental Health
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. The standard classification reference used by mental health professionals in the United States to diagnose psychiatric conditions, including substance use disorders.
Dysphoria Mental Health
A state of profound unease, dissatisfaction, or emotional distress. The opposite of euphoria. Often experienced during withdrawal and early recovery.