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Is Addiction Genetic?

Is Addiction Genetic?

When exploring possible causes of addiction, genetic factors are often brought into focus. But, is addiction genetic?

Yes, there are some genetic factors that may make an individual more susceptible to developing an addiction. One study showed that at least half of a person’s risk for developing an addiction is linked to genetic factors. 1 This includes personality type predispositions and variations in brain structure that, with more studies, may be proven to increase a person’s risk of becoming an addict.

Many famous people in recovery and everyday people who are struggling with addiction may have genetic factors that make them more susceptible to addiction. We explore the possible genetic causes of addiction and alcoholism and offer insight for treating these challenges.

Is there a Genetic Predisposition to Addiction?

Certain dopamine receptors in the brain may soon shed light on a person’s risks of struggling with alcoholism or drug addiction. Brain studies suggest that people with fewer dopamine receptors for D2 are more likely to struggle with addiction. The number of D2 dopamine receptors in the brain is largely influenced by a person’s genes, making this a potential genetic factor in risk of addiction. 1

Another gene-influenced brain region is the strength of mu-opioid receptors in the brain. Some people have a genetic variant where these receptors have three times the affinity for absorption of endorphins, making them more susceptible to alcohol and heroin addiction. 2

Genes, Behavior, and Addiction

Genes influence everything about us, even our behaviors. Certain gene sequences with HTR2B receptors increase a person’s risk of impulsive behaviors.3 Though these individuals may not have a genetic predisposition to addiction itself, their predisposition to behaviors such as risk taking actions may result in use of drugs that soon leads to addiction.

Treating Addiction

While scientists are still identifying the numerous genetic causes of addiction, sobriety is still possible. Understanding the genetic influences of addiction can help patients get the specific treatments they need for sobriety.

We offer treatment, detox, relapse prevention, and rehab scholarships to help patients heal. Call 888-280-4763 to learn more about our treatment opportunities.


  1. American Psychological Association – Genes matter in addiction
  2. Harvard health – Questions & Answers: Is addiction hereditary?
  3. NCBI – The Genetic Basis of Addictive Disorders
Alyssa, Director of Digital Marketing
Alyssa, Director of Digital Marketing
Alyssa is the National Director of Digital Marketing and is responsible for a multitude of integrated campaigns and events in the behavioral health and addictions field. All articles have been written by Alyssa and medically reviewed by our Chief Medical Officer, Dr. Darrin Mangiacarne.
Is Addiction Genetic?
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